For non-surgical removal of mast cell tumors (MCT)
STELFONTA destroys 87% of mast cell tumors with 1 or 2 injections,1 2 so your dog can return to their usual self as soon as possible. However, not all dogs or tumors are suited to STELFONTA.
STELFONTA was approved by the FDA in 2020 to treat all grades of mast cell tumors, as long as they have not yet spread to other areas of the body (metastasized).6
Ask your vet whether your dog is a suitable candidate for STELFONTA. The tumor should be:
STELFONTA should not be injected into mast cell tumors that are underneath the skin (subcutaneous) and located above the elbow or hock (e.g. on the body, head, or neck) as necrotic debris from the injected tumor may accumulate in the subcutaneous space, increasing the risk of systemic adverse reactions, including death, from mast cell degranulation. STELFONTA can treat tumors on the surface of the skin all over the body.
STELFONTA destroys mast cell tumors by disrupting the cell membrane and cutting off it’s blood supply. It also stimulates the dog’s immunity to fight the cancer. The tumor then detaches from the healthy tissue and falls away, leaving a temporary wound and healthy tissue where the tumor once was.
These wounds typically heal within 4 to 6 weeks without intervention. In some cases the wound is extensive and may take longer to fully heal. A wound is just one sign STELFONTA is working and the tumor is destroyed.
Can the tumor be graded? Because STELFONTA stimulates the immune system to destroy mast cell tumors, it is not possible to send the tumor off for histopathological grading in the same manner as surgically removed tumors. However, cytological grading can be undertaken via a fine needle aspirate prior to treatment if desired.1
Lucy
BREED American Eskimo
AGE 12 yrs
TUMOR 5cm³ on her thigh
*Within 2 hours, you’ll be able to see STELFONTA working as the tumor starts to swell and change colour. Within 4 hours the tumor starts to necrose.1,4,5 STELFONTA acts quickly to break down the tumor cell walls, activate the immune system and block blood vessels that feed the tumor.
With successful treatment, the tumor will essentially fall away and an empty pocket, or open wound, will remain where the tumor used to be. Don’t worry. This is normal, and healthy new skin will grow and close over. Most wounds do not need to be covered and heal naturally.
Within 14 days pet owners say their dogs are back to their pre diagnosis quality of life.
Pet owner reviews his STELFONTA experience: Paul’s dog Brooklyn had a tumor on her ear which he elected to treat with STELFONTA. “I hate the cropped and docked look, so I was excited when I first learned about STELFONTA when researching options and relieved when Dr. Sue Cancer Vet said Brooklyn was a candidate”. After a successful STELFONTA treatment, Paul reports Brooklyn is back to her healthy, happy, sassy self, and shares his tips for the journey:
FDA-CVM WARNING: SEVERE WOUND FORMATION IN HUMANS; EXTENSIVE WOUND FORMATION, MAST CELL DEGRANULATION, AND DEATH IN DOGS DUE TO MAST CELL DEGRANULATION
Human Safety
Dog Safety
IMPORTANT SAFETY INFORMATION
Formation of wounds, possibly extensive, is an intended and likely response to treatment with STELFONTA along with associated swelling, bruising and pain; these wounds are expected to heal. Appropriate pre- and post-treatment medications must be given, including a corticosteroid plus blocking agents for both H1 and H2 receptors, in order to decrease the potential for severe systemic adverse reactions, including death, from mast cell degranulation.
You are entering a US-hosted site for the use of STELFONTA (tigilanol tiglate injection) in the United States of America. All information pertains to the US product label.